Prosci/4E-BP1 Antibody [11G12C11]/32-103/0.1 mg,ProSci,,ProSci,prosci-inc,ProSci Incorporated,+,,Array.Array.Array蚂蚁淘厂家直采.

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ProSci Inc

主营：二抗，重组蛋白，细胞和组织裂解液，细胞涂片，组织切片，多肽

℡ 4000-520-616

产品编号：32-103

市场价：¥6500.00

场地：美国(厂家直采)

产品分类：抗体类>一抗>重组抗体>

联系QQ：1570468124

电话号码：4000-520-616

邮箱： info@ebiomall.com

美元价：$325.00

品牌： ProSci

公司：ProSci Inc

公司分类：

商品介绍

SPECIESREACTIVITY:	Human
TESTEDAPPLICATIONS:	IHC
APPLICATIONS:	IHC:1:500-1:1,000 ELISA:Proposedilution1:10,000. Determiningoptimalworkingdilutionsbytitrationtest.
USERNOTE:	Optimaldilutionsforeachapplicationtobedeterminedbytheresearcher.
IMMUNOGEN:	Ni-NTApurifiedtruncatedrecombinant4EBP1expressedinE.ColistrainBL21(DE3).
HOSTSPECIES:	Mouse

PURIFICATION:	AntibodyispurifiedbyproteinAaffinitychromatography.
BUFFER:	PurifiedantibodyinPBScontaining0.03%sodiumazide.
STORAGECONDITIONS:	4E-BP1monoclonalantibodycanbestoredat-20˚C,stableforoneyear.Aswithallantibodiescareshouldbetakentoavoidrepeatedfreezethawcycles.Antibodiesshouldnotbeexposedtoprolongedhightemperatures.
CLONALITY:	Monoclonal
ISOTYPE:	IgG1
CONJUGATE:	Unconjugated

ALTERNATENAMES:	Phosphorylatedheat-andacid-stableproteinregulatedbyinsulin1,4E-BP1,BP-1,4EBP1,PHAS-I
ACCESSIONNO.:	Q13541
PROTEINGINO.:	34921508
OFFICIALSYMBOL:	EIF4EBP1
GENEID:	1978

BACKGROUND:	4E-BP1(eukaryotictranslationInitiationFactor4EBindingProtein1),alsocalledELF4EBP1/BP-1/PHAS-I,whichislocatedonchromosome8p12,with118-aminoacidprotein(about13kDa).BindingofeIF4EBP1toeIF4EisreversIBLeandisdependentonthephosphorylationstatusofeIF4EBP1.NonphosphorylatedeIF4EBP1willbindstronglytoeIF4Ewhile(24kDa),thephosphorylatedformwillnot.Akt,TOR,MAPkinase,S6kinase,andCdc2areknownkinasescapableofinactivatingeIF4EBP1bindingtoeIF4Ebyphosphorylatingeitherthreonines35,45,69orserine64.Although,notallphosphorylationeventsequallyblocktheeIF4EBP1-eIF4Einteraction.
REFERENCES:	1)Pause,A.etal.1994.Nature.371:762–767.
	2)Fadden,P.etal.1997.J.Biol.Chem.272:10240–10247.

品牌介绍

ProSci Inc.始终开放以支持研究需求，同时确保我们员工的健康和安全。ProSci拥有广泛的冠状病毒SARS-CoV-2 重组蛋白和抗体产品组合，并将继续积极开发新的冠状病毒产品。此外，ProSci的定制抗体服务也保持开放状态，以支持研究团体开发研究工具，诊断，疗法和疫苗。