SPECIES: | Human |
---|---|
SOURCESPECIES: | HumanCells |
SEQUENCE: | Glu20-Lys368 |
FUSIONTAG: | C-6Histag |
TESTEDAPPLICATIONS: | |
APPLICATIONS: | ThisrecombinantproteincanbeusedforBIOLOGicalassays.Forresearchuseonly. |
PURITY: | Greaterthan95%asdeterminedbyreducingSDS-PAGE. Endotoxinlevellessthan0.1ng/ug(1IEU/ug)asdeterminedbyLALtest. |
---|---|
PREDICTEDMOLECULARWEIGHT: | 40.47kD |
PHYSICALSTATE: | Lyophilized |
BUFFER: | Lyophilizedfroma0.2umfilteredsolutionof20mMPB,150mMNaCl,pH7.2.Itisnotrecommendedtoreconstitutetoaconcentrationlessthan100ug/ml.DissolvethelyophilizedproteininddH2O. |
STORAGECONDITIONS: | Lyophilizedproteinshouldbestoredat-20˚C,thoughstableatroomtemperaturefor3weeks. Reconstitutedproteinsolutioncanbestoredat4-7˚Cfor2-7days. Aliquotsofreconstitutedsamplesarestableat-20˚Cfor3months. |
ALTERNATENAMES: | Biglycan,Bone/CartilageProteoglycanI,PG-S1,BGN,SLRR1A |
---|---|
ACCESSIONNO.: | P21810 |
PROTEINGINO.: | 578877726 |
Biglycanisa200-350kDproteoglycanconsistingofa45kDcoreproteinandtwochrondroitin/dermatansulfateglycosaminoglycanchains.BiglycanbindstoTGF-ß.ItalsobindstocollagentypeIinlowionicstrength(lessthan3mMphosphate)buffer.Athigherionicstrengths,BiglycandoesnotbindtocollagentypeI.ItenhancestheinhibitioneffectofTGF-ßonosteoclastproliferationataconcentrationof4-20mg/ml.ItalsopreventstheattachmentofCHOcellstofibronectin,witha50%inhibitionat17-21mg/ml. |
ProSci Inc.始终开放以支持研究需求,同时确保我们员工的健康和安全。ProSci拥有广泛的冠状病毒SARS-CoV-2 重组蛋白和抗体产品组合, 并将继续积极开发新的冠状病毒 产品。此外,ProSci的定制抗体服务也保持开放状态,以支持研究团体开发 研究工具,诊断,疗法和疫苗。