Prosci/Acinus Antibody/2241/0.1 mg,ProSci,,ProSci,prosci-inc,ProSci Incorporated,+,,Array.Array.Array蚂蚁淘厂家直采.

产品编号：2241

市场价：¥6500.00

场地：美国(厂家直采)

产品分类：抗体类>一抗>重组抗体>

联系QQ：1570468124

电话号码：4000-520-616

邮箱： info@ebiomall.com

美元价：$325.00

品牌： ProSci

公司：ProSci Inc

公司分类：

商品介绍

SPECIESREACTIVITY:	Human
HOMOLOGY:	Predictedspeciesreactivitybasedonimmunogensequence:Mouse:(100%)
TESTEDAPPLICATIONS:	ELISA,IF,WB
APPLICATIONS:	AcinusantibodycanbeusedfordetectionofacinusbyWesternblotat1μg/mL.Anapproximate220kDabandcanbedetected.Forimmunofluorescencestartat20μg/mL.
USERNOTE:	Optimaldilutionsforeachapplicationtobedeterminedbytheresearcher.
POSITIVECONTROL:	1)Cat.No.1204-K562CellLysate
PREDICTEDMOLECULARWEIGHT:	220kDa
IMMUNOGEN:	Acinusantibodywasraisedagainsta16aminoacidpeptidenearthecarboxyterminusofhumanAcinus. Theimmunogenislocatedwithinaminoacids980-1030ofAcinus.
HOSTSPECIES:	Rabbit

PURIFICATION:	AcinusAntibodyisaffinitychromatographypurifiedviapeptidecolumn.
PHYSICALSTATE:	Liquid
BUFFER:	AcinusAntibodyissuppliedinPBScontaining0.02%sodiumazide.
STORAGECONDITIONS:	Acinusantibodycanbestoredat4˚Cforthreemonthsand-20˚C,stableforuptooneyear.Aswithallantibodiescareshouldbetakentoavoidrepeatedfreezethawcycles.Antibodiesshouldnotbeexposedtoprolongedhightemperatures.
CLONALITY:	Polyclonal
ISOTYPE:	IgG
CONJUGATE:	Unconjugated

ALTERNATENAMES:	AcinusAntibody:ACN,ACINUS,fSAP152,KIAA0670,Apoptoticchromatincondensationinducerinthenucleus,Acinus
ACCESSIONNO.:	AAD56724
PROTEINGINO.:	5931959
OFFICIALSYMBOL:	ACIN1
GENEID:	22985

BACKGROUND:	AcinusAntibody:Chromatincondensationandnuclearfragmentation(CCNF)isthehallmarkofapoptosis.CCNFistriggeredbytheactivationofmembersofcaspasefamily,caspaseactivatedDNase(CAD/DFF40),andseveralnovelproteinsincludingAIFandCIDE.AnewinducerofchromatincondensationwasrecentlyidentifiedanddesignatedAcinus(forapoptoticchromatincondensationinducerinthenucleus).Acinusiscleavedbycaspase-3andanadditionalunknownproteasegeneratingasmallactivepeptidep17,whichcauseschromatincondensationinvitrowhenitisaddedtopurifiednuclei.Acinusalsoinducesapoptoticchromatincondensationincells.Acinusisubiquitouslyexpressed.ThreedifferentsplicedformsofAcinushavebeenidentifiedinhumanandmouseanddesignatedAcinusL,AcinusSandAcinusS".
REFERENCES:	1)ZamzamiN,KroemerG.Condensedmatterincelldeath.Nature1999;401:127-8.
	2)SaharaS,AotoM,EguchiY,ImamotoN,YonedaY,TsujimotoY.Acinusisacaspase-3-activatedproteinrequiredforapoptoticchromatincondensation.Nature1999401:168-73.

品牌介绍

ProSci Inc.始终开放以支持研究需求，同时确保我们员工的健康和安全。ProSci拥有广泛的冠状病毒SARS-CoV-2 重组蛋白和抗体产品组合，并将继续积极开发新的冠状病毒产品。此外，ProSci的定制抗体服务也保持开放状态，以支持研究团体开发研究工具，诊断，疗法和疫苗。