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主营:二抗,重组蛋白,细胞和组织裂解液,细胞涂片,组织切片,多肽
℡ 4000-520-616
℡ 4000-520-616
Prosci/ABCB5 Recombinant Protein/92-176/0.05 mg
产品编号:92-176
市  场 价:¥10500.00
场      地:美国(厂家直采)
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$525.00
品      牌: ProSci
公      司:ProSci Inc
公司分类:
Prosci/ABCB5 Recombinant Protein/92-176/0.05 mg
商品介绍

Specifications

SPECIES:Human
SOURCESPECIES:E.coli
SEQUENCE:Ile141-Val247
FUSIONTAG:N-Trxtag
TESTEDAPPLICATIONS:
APPLICATIONS:ThisrecombinantproteincanbeusedforBIOLOGicalassays.Forresearchuseonly.

Properties

PURITY:Greaterthan95%asdeterminedbyreducingSDS-PAGE.
Endotoxinlevellessthan0.1ng/ug(1IEU/ug)asdeterminedbyLALtest.
PREDICTEDMOLECULARWEIGHT:29.4kD
PHYSICALSTATE:Lyophilized
BUFFER:Lyophilizedfroma0.2umfilteredsolutionof20mMPB,150mMNaCl,pH7.4.Itisnotrecommendedtoreconstitutetoaconcentrationlessthan100ug/ml.DissolvethelyophilizedproteininddH2O.
STORAGECONDITIONS:Lyophilizedproteinshouldbestoredat-20˚C,thoughstableatroomtemperaturefor3weeks.
Reconstitutedproteinsolutioncanbestoredat4-7˚Cfor2-7days.
Aliquotsofreconstitutedsamplesarestableat-20˚Cfor3months.

AdditionalInfo

ALTERNATENAMES:ATP-bindingcassettesub-familyBmember5,P-glycoproteinABCB5,ABCB5P-gp,ABCB5
ACCESSIONNO.:Q2M3G0

Background

ATP-bindingcassettesub-familyBmember5(ABCB5)isaplasmamembrane-spanningprotein.ABCB5isprincipallyexpressedinphysiologicalskinandhumanmalignantmelanoma.ABCB5hasbeensuggestedtoregulateskinProgenitorcellfusionandmediatechemotherapeuticdrugresistanceinstem-liketumorcellsubpopulationsinhumanmalignantmelanoma.Itiscommonlyover-expressedoncirculatingmelanomatumourcells.FurThermore,theABCB5+melanoma-initiatingcellsweredemonstratedtoexpressFLT1(VEGFR1)receptortyrosinekinasewhichwasfunctionallyrequiredforefficientxenografttumorformation,asdemonstratedbyshRNAknockdownexperiments.
品牌介绍

ProSci Inc.始终开放以支持研究需求,同时确保我们员工的健康和安全。ProSci拥有广泛的冠状病毒SARS-CoV-2 重组蛋白和抗体产品组合,  并将继续积极开发新的冠状病毒  产品。此外,ProSci的定制抗体服务也保持开放状态,以支持研究团体开发  研究工具,诊断,疗法和疫苗。

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