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主营:二抗,重组蛋白,细胞和组织裂解液,细胞涂片,组织切片,多肽
℡ 4000-520-616
℡ 4000-520-616
Prosci/Adiponectin Recombinant Protein/40-328/0.005 mg
产品编号:40-328
市  场 价:¥3100.00
场      地:美国(厂家直采)
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$155.00
品      牌: ProSci
公      司:ProSci Inc
公司分类:
Prosci/Adiponectin Recombinant Protein/40-328/0.005 mg
商品介绍

Specifications

SPECIES:Human
SOURCESPECIES:High-5Insectcells
SEQUENCE:RGHHHHHHHHETTTQGPGVLLPLPKGACTGWMAGIPGHPGHNGAPGRDGRDGTPGEKGEKGDPGLIGPKGDIGETGVPGAEGPRGFPGIQGRKGEPGEGAYVYRSAFSVGLETYVTIPNMPIRFTKIFYNQQNHYDGSTGKFYCNIPGLYYFSYHITVYMKDVKVSLFKKDKAVLFTYDQYQEKNVDQASGSVLLHLEVGDQVWLQVYGDGDHNGLYADNVNDSTFTGFLLYHDTN
TESTEDAPPLICATIONS:
BIOLOGICALACTIVITY:BiologicalactivitywasdeterminedbyacytotoxicassayusingM1cells.TheED50forthiseffectis3.0-6.0μg/mL.

Properties

PURITY:Greaterthan97%bySDS-PAGEgelandHPLCanalyses.

Endotoxinlevelislessthan0.1ngperμg(1EU/μg).
PHYSICALSTATE:Lyophilized
STORAGECONDITIONS:ThelyophilizedADIponectinrecombinantproteinisstableforatleast2yearsfromdateofreceiptat-20˚C.ReconstitutedAdiponectinisstableforatleast3monthswhenstoredinworkingaliquotswithacarrierproteinat-20˚C.Aswithanyprotein,exposingAdiponectinrecombinantproteintorepeatedfreeze/thawcyclesisnotrecommended.Whenworkingwithproteinscareshouldbetakentokeeprecombinantproteinatacoolandstabletemperature.

AdditionalInfo

ALTERNATENAMES:ACDC,ADPN,APM1,APM-1,GBP28,ACRP30,ADIPQTL1,ACDC,Adiponectin,30kDaadipocytecomplement-relatedprotein
ACCESSIONNO.:NP_001171271.1
PROTEINGINO.:295317372

Background

Adiponectinisanadipose-derivedsecretedproteincontaining226aminoacidresidues.Itisrelativelyabundantinhumansandrodents,accountingforabout0.01%oftotalplasmaprotein.Thecirculatinglevelsofadiponectinaredecreasedunderconditionsofobesity,insulinresistance,andtypeIIdiabetes.Disruptionofadiponectininmicecausesinsulinresistanceandneointimalformation.Conversely,admiNISTrationofrecombinantadiponectinsuppresseshepaticglucoseproduction,andreversesinsulinresistanceassociatedwithbothlipoatrophyandobesity.Theprotectiveroleofadiponectinisattributedtoitsanti-inflammatoryproperties(e.g.ABIlitytosuppressexpressionofTNF-αandclassAscavengerreceptorinmacrophages).RecombinantadiponectinisamultimericglycoproteincontainingaminoacidsGlu-19toAsn-244oftheadiponectinprecursorproteinfusedtoanN-terminalhistidinetag.Monomericglycosylatedadiponectinmigratesatanapparentmolecularweightofapproximately25.9kDabySDSPAGEanalysisunderreducingconditions.
品牌介绍

ProSci Inc.始终开放以支持研究需求,同时确保我们员工的健康和安全。ProSci拥有广泛的冠状病毒SARS-CoV-2 重组蛋白和抗体产品组合,  并将继续积极开发新的冠状病毒  产品。此外,ProSci的定制抗体服务也保持开放状态,以支持研究团体开发  研究工具,诊断,疗法和疫苗。

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