SPECIES REACTIVITY: | Human |
---|---|
TESTED APPLICATIONS: | WB |
APPLICATIONS: | For WB starting dilution is: 1:1000 |
USER NOTE: | Optimal dilutions for each application to be determined by the researcher. |
PREDICTED MOLECULAR WEIGHT: | 47 kDa |
IMMUNOGEN: | This AADAT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 196-224 amino acids from the Central region of human AADAT. |
HOST SPECIES: | Rabbit |
PURIFICATION: | This antibody is purified through a protein A column, followed by peptide affinity purification. |
---|---|
PHYSICAL STATE: | Liquid |
BUFFER: | Supplied in PBS with 0.09% (W/V) sodium azide. |
CONCENTRATION: | 0.5 mg/ml |
STORAGE CONDITIONS: | Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
CLONALITY: | Polyclonal |
ISOTYPE: | Rabbit Ig |
CONJUGATE: | Unconjugated |
ALTERNATE NAMES: | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial, KAT/AadAT, 2-aminoadipate aminotransferase, 2-aminoadipate transaminase, Alpha-aminoadipate aminotransferase, AadAT, Kynurenine aminotransferase II, Kynurenine--oxoglutarate aminotransferase II, Kynurenine--oxoglutarate transaminase 2, Kynurenine--oxoglutarate transaminase II, AADAT, KAT2 |
---|---|
ACCESSION NO.: | Q8N5Z0 |
PROTEIN GI NO.: | 46395904 |
OFFICIAL SYMBOL: | AADAT |
GENE ID: | 51166 |
BACKGROUND: | This gene encodes a protein that is highly similar to mouse and rat kynurenine aminotransferase II. The rat protein is a homodimer with two transaminase activities. One activity is the transamination of alpha-aminoadipic acid, a final step in the saccaropine pathway which is the major pathway for L-lysine catabolism. The other activity involves the transamination of kynurenine to produce kynurenine acid, the precursor of kynurenic acid which has neuroprotective properties. Two alternative transcripts encoding the same isoform have been identified, however, additional alternative transcripts and isoforms may exist. |
---|---|
REFERENCES: | 1) Han, Q., et al. Biosci. Rep. 28(4):205-215(2008) | 2) Rossi, F., et al. J. Biol. Chem. 283(6):3559-3566(2008) | 3) Han, Q., et al. J. Biol. Chem. 283(6):3567-3573(2008) | 4) Lamesch, P., et al. Genomics 89(3):307-315(2007) |
ProSci Inc.始终开放以支持研究需求,同时确保我们员工的健康和安全。ProSci拥有广泛的冠状病毒SARS-CoV-2 重组蛋白和抗体产品组合, 并将继续积极开发新的冠状病毒 产品。此外,ProSci的定制抗体服务也保持开放状态,以支持研究团体开发 研究工具,诊断,疗法和疫苗。