SPECIES: | Human |
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SOURCE SPECIES: | E. coli |
SEQUENCE: | Met1-Pro327 |
FUSION TAG: | Tag Free |
TESTED APPLICATIONS: | |
APPLICATIONS: | This recombinant protein can be used for biological assays. For research use only. |
PURITY: | Greater than 95% as determined by reducing SDS-PAGE. Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test. |
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PREDICTED MOLECULAR WEIGHT: | 36.9 kD |
PHYSICAL STATE: | Lyophilized |
BUFFER: | Lyophilized from a 0.2 um filtered solution of 20mM PB, 150mM NaCl, pH 7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O. |
STORAGE CONDITIONS: | Lyophilized protein should be stored at -20˚C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7˚C for 2-7 days. Aliquots of reconstituted samples are stable at -20˚C for 3 months. |
ALTERNATE NAMES: | Annexin A8, Annexin VIII, Annexin-8, Vascular Anticoagulant-Beta, VAC-Beta, ANXA8, ANX8 |
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ACCESSION NO.: | P13928 |
PROTEIN GI NO.: | 524552373 |
Annexin A8 (ANXA8) belongs to a family of calcium-dependent membrane and phospholipid binding proteins. Annexin A8 contains 4 annexin repeats separated by linking sequences of variable lengths. A pair of annexin repeats may form one binding site for calcium and phospholipid. ANXA8 is preferentially expressed in acute promyelocytic leukemia (APL) cells, which suggests its participation in hematopoietic cell differentiation. In addition, ANXA8 is an anticoagulant protein that acts as an indirect inhibitor of the thromboplastin-specific complex, which is involved in the blood coagulation cascade. |
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