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主营:二抗,重组蛋白,细胞和组织裂解液,细胞涂片,组织切片,多肽
℡ 4000-520-616
℡ 4000-520-616
Prosci/B Lymphocyte Kinase Recombinant Protein/92-107/0.05 mg
产品编号:92-107
市  场 价:¥8500.00
场      地:美国(厂家直采)
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$425.00
品      牌: ProSci
公      司:ProSci Inc
公司分类:
Prosci/B Lymphocyte Kinase Recombinant Protein/92-107/0.05 mg
商品介绍

Specifications

SPECIES:Human
SOURCESPECIES:E.coli
SEQUENCE:Gly2-Pro505
FUSIONTAG:C-6Histag
TESTEDAPPLICATIONS:
APPLICATIONS:ThisrecombinantproteincanbeusedforBIOLOGicalassays.Forresearchuseonly.

Properties

PURITY:Greaterthan95%asdeterminedbyreducingSDS-PAGE.
Endotoxinlevellessthan0.1ng/ug(1IEU/ug)asdeterminedbyLALtest.
PREDICTEDMOLECULARWEIGHT:58.7kD
PHYSICALSTATE:Liquid
BUFFER:Suppliedasa0.2umfilteredsolutionof20mMTris,500mMNaCl,1mMDTT,pH7.4.Itisnotrecommendedtoreconstitutetoaconcentrationlessthan100ug/ml.DissolvethelyophilizedproteininddH2O.
STORAGECONDITIONS:Storeat-20˚C,stablefor6monthsafterreceipt.
Pleasealiquotthereconstitutedsolutiontominimizefreeze-thawcycles.

AdditionalInfo

ALTERNATENAMES:Tyrosine-ProteinKinaseBlk,BLymphocyteKinase,p55-Blk,BLK
ACCESSIONNO.:P51451

Background

Tyrosine-ProteinKinaseBlk(BLK)containsoneproteinkinasedomain,oneSH2domainandoneSH3domain.BLKisanon-receptortyrosinekinase,whichisinvolvedinB-lymphocytedevelopment,differentiationandsignaling.B-cellreceptor(BCR)signalingrequiresatightregulationofseveralproteintyrosinekinasesandphosphatases,andassociatedcoreceptors.SignalingthroughBLKplaysanimportantroleintransmittingsignalsthroughsurfaceimmunoglobulinesandsupportsthepro-Btopre-Btransition,aswellasthesignalingforgrowtharrestandapoptosisdownstreamofB-cellreceptor.DefectsinBLKareacauseofmaturity-onsetdiabetesoftheyoungtype11(MODY11).
品牌介绍

ProSci Inc.始终开放以支持研究需求,同时确保我们员工的健康和安全。ProSci拥有广泛的冠状病毒SARS-CoV-2 重组蛋白和抗体产品组合,  并将继续积极开发新的冠状病毒  产品。此外,ProSci的定制抗体服务也保持开放状态,以支持研究团体开发  研究工具,诊断,疗法和疫苗。

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