SPECIES: | Human |
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SOURCE SPECIES: | HEK293 cells |
SEQUENCE: | Phe 33 - Ala 194 |
FUSION TAG: | His Tag |
TESTED APPLICATIONS: | WB |
APPLICATIONS: | This recombinant protein can be used for WB. For research use only. |
PURITY: | >95% as determined by SDS-PAGE. Endotoxin level is less than 1.0 EU per ug by the LAL method. |
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PREDICTED MOLECULAR WEIGHT: | 20 kDa |
PHYSICAL STATE: | Lyophilized |
BUFFER: | PBS, pH7.4 |
STORAGE CONDITIONS: | Lyophilized Protein should be stored at -20˚C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚C or -70˚C. Avoid repeated freeze-thaw cycles. |
ALTERNATE NAMES: | B7-H5,SISP1,Gi24,VISTA |
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ACCESSION NO.: | AAH20568 |
Platelet receptor Gi24, also known as B7-H5 and stress-induced secreted protein-1 (Sisp-1), is a protein that in humans is encoded by the C10orf54 gene, which contains 1 Ig-like (immunoglobulin-like) domain. As for C10orf54 gene, C10orf54 appears to positively interact with BMP-4, potentiating BMP signaling and the transition from an undifferentiated to a differentiated state on ESCs. Human C10orf54 undergoes proteolytic cleavage by MT1-MMP, generating a soluble 30 kDa extracellular fragment plus a 25-30 kDa membrane-bound fragment. |
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