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主营:二抗,重组蛋白,细胞和组织裂解液,细胞涂片,组织切片,多肽
℡ 4000-520-616
℡ 4000-520-616
Prosci/ACK1 Antibody/63-155/400 ul
产品编号:63-155
市  场 价:¥7500.00
场      地:美国(厂家直采)
产品分类: 抗体类>一抗>重组抗体>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$375.00
品      牌: ProSci
公      司:ProSci Inc
公司分类:
Prosci/ACK1 Antibody/63-155/400 ul
商品介绍

Specifications

SPECIESREACTIVITY:Human
HOMOLOGY:Predictedspeciesreactivitybasedonimmunogensequence:Bovine
TESTEDAPPLICATIONS:IHC-P,WB
APPLICATIONS:ForWBstartingdilutionis:1:1000

ForIHC-Pstartingdilutionis:1:50~100
USERNOTE:Optimaldilutionsforeachapplicationtobedeterminedbytheresearcher.
PREDICTEDMOLECULARWEIGHT:115kDa
IMMUNOGEN:ThisACK1antibodyisgeneratedfromrabbitsimmunizedwithaKLHconjugatedsyntheticpeptidebetween934-964aminoacidsfromtheC-terminalregionofhumanACK1.
HOSTSPECIES:Rabbit

Properties

PURIFICATION:ThisantibodyispurifiedthroughaproteinAcolumn,followedbypeptideaffinitypurification.
PHYSICALSTATE:Liquid
BUFFER:SuppliedinPBSwith0.09%(W/V)sodiumazide.
CONCENTRATION:0.42mg/ml
STORAGECONDITIONS:Storeat4˚Cforthreemonthsand-20˚C,stableforuptooneyear.Aswithallantibodiescareshouldbetakentoavoidrepeatedfreezethawcycles.Antibodiesshouldnotbeexposedtoprolongedhightemperatures.
CLONALITY:Polyclonal
ISOTYPE:RabbitIg
CONJUGATE:Unconjugated

AdditionalInfo

ALTERNATENAMES:ActivatedCDC42kinase1,ACK-1,Tyrosinekinasenon-receptorprotein2,TNK2,ACK1
ACCESSIONNO.:Q07912
PROTEINGINO.:229462980
OFFICIALSYMBOL:TNK2
GENEID:10188

Background

BACKGROUND:ACK1isatyrosinekinasethatbindsCdc42HsinitsGTP-boundformandinhibitsboththeintrinsicandGTPase-activatingprotein(GAP)-stimulatedGTPaseactivityofCdc42Hs.Thisbindingismediatedbyauniquesequenceof47aminoacidsC-terminaltoanSH3domain.TheproteinmaybeinvolvedinaregulatorymechanismthatsustainstheGTP-boundactiveformofCdc42Hsandwhichisdirectlylinkedtoatyrosinephosphorylationsignaltransductionpathway.
REFERENCES:1)Yokoyama,N.,etal.,J.Biol.Chem.278(48):47713-47723(2003).
2)Manser,E.,etal.,Nature363(6427):364-367(1993).
品牌介绍

ProSci Inc.始终开放以支持研究需求,同时确保我们员工的健康和安全。ProSci拥有广泛的冠状病毒SARS-CoV-2 重组蛋白和抗体产品组合,  并将继续积极开发新的冠状病毒  产品。此外,ProSci的定制抗体服务也保持开放状态,以支持研究团体开发  研究工具,诊断,疗法和疫苗。

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