SPECIES: | Human |
---|---|
SOURCESPECIES: | E.coli |
SEQUENCE: | DGNSTRSPETNGLLCGDPEENCAATTTQSKRKGHFSRCPKQYKHYCIKGRCRFVVAEQTPSCVCDEGYIGARCERVDLFY |
TESTEDAPPLICATIONS: | |
BIOLOGICALACTIVITY: | TheED50wasdeterminedbythedose-dependentstimulationoftheproliferationofmurineBalb/3T3cellsis≤0.05ng/mL,correspondingtoaspecificactivityof≥2x107units/mg. |
PURITY: | Greaterthan98%bySDS-PAGEgelandHPLCanalyses. Endotoxinlevelislessthan0.1ngperμg(1EU/μg). |
---|---|
PHYSICALSTATE: | Lyophilized |
STORAGECONDITIONS: | ThelyophilizedBetacellulinrecombinantproteinisstableforatleast2yearsfromdateofreceiptat-20˚C.ReconstitutedBetacellulinisstableforatleast3monthswhenstoredinworkingaliquotswithacarrierproteinat-20˚C.Aswithanyprotein,exposingBetacellulinrecombinantproteintorepeatedfreeze/thawcyclesisnotrecommended.Whenworkingwithproteinscareshouldbetakentokeeprecombinantproteinatacoolandstabletemperature. |
ALTERNATENAMES: | Probetacellulin,BTC |
---|---|
ACCESSIONNO.: | NP_001720.1 |
PROTEINGINO.: | 4502461 |
BetacellulinisanEGF-relatedpolypeptidegrowthfactorthatsignalsthroughtheEGFreceptor.Itisproducedinseveraltissues,includingthepancreas,smallintestine,andincertaintumorcells.Betacellulinisapotentmitogenforretinalpigmentepithelialcellsandvascularsmoothmusclecells.HumanBetacellulinisinitiallysynthesizedasaglycosylated32.0kDatransmembraneprecursorprotein,whichisprocessedbyproteolyticcleavagetoproducethematuresequence.RecombinanthumanBetacellulinisa9.0kDamonomericprotein,containing80aminoresidues,whichcomprisesthematureEGFhomologousportionoftheBetacellulinprotein. |
ProSci Inc.始终开放以支持研究需求,同时确保我们员工的健康和安全。ProSci拥有广泛的冠状病毒SARS-CoV-2 重组蛋白和抗体产品组合, 并将继续积极开发新的冠状病毒 产品。此外,ProSci的定制抗体服务也保持开放状态,以支持研究团体开发 研究工具,诊断,疗法和疫苗。