SPECIES: | Murine |
---|---|
SOURCESPECIES: | E.coli |
SEQUENCE: | DGNTTRTPETNGSLCGAPGENCTGTTPRQKVKTHFSRCPKQYKHYCIHGRCRFVVDEQTPSCICEKGYFGARCERVDLFY |
TESTEDAPPLICATIONS: | |
BIOLOGICALACTIVITY: | BiologicalactivitywasdeterminedbyitsABIlitytostimulatetheproliferationofmouseBalb/3T3cells.TheexpectedED50is≤0.01ng/mL,correspondingtoaspecificactivityof≥1x108units/mg.Endotoxinlevelislessthan0.1ngperμg(1EU/μg). |
PURITY: | Greaterthan98%bySDS-PAGEgelandHPLCanalyses. |
---|---|
PHYSICALSTATE: | Lyophilized |
STORAGECONDITIONS: | ThelyophilizedBetacellulinrecombinantproteinisstableforatleast2yearsfromdateofreceiptat-20˚C.ReconstitutedBetacellulinstableforatleast3monthswhenstoredinworkingaliquotswithacarrierproteinat-20˚C.Aswithanyprotein,exposingBetacellulinrecombinantproteintorepeatedfreeze/thawcyclesisnotrecommended.Whenworkingwithproteinscareshouldbetakentokeeprecombinantproteinatacoolandstabletemperature. |
ALTERNATENAMES: | Bcn,Bcn,Probetacellulin,BTC |
---|---|
ACCESSIONNO.: | NP_031594.1 |
PROTEINGINO.: | 6680812 |
BetacellulinisanEGF-relatedpolypeptidegrowthfactorthatsignalsthroughtheEGFreceptor.Itisproducedinseveraltissues,includingthepancreas,smallintestine,andincertaintumorcells.Betacellulinisapotentmitogenforretinalpigmentepithelialcellsandvascularsmoothmusclecells.Betacellulinisinitiallysynthesizedasaglycosylated32.0kDatransmembraneprecursorprotein,whichisprocessedbyproteolyticcleavagetoproducethematuresequence.RecombinantmurineBetacellulinisa9.0kDamonomericprotein,containing80aminoresidues,whichcomprisesthematureEGFhomologousportionoftheBetacellulinprotein. |
ProSci Inc.始终开放以支持研究需求,同时确保我们员工的健康和安全。ProSci拥有广泛的冠状病毒SARS-CoV-2 重组蛋白和抗体产品组合, 并将继续积极开发新的冠状病毒 产品。此外,ProSci的定制抗体服务也保持开放状态,以支持研究团体开发 研究工具,诊断,疗法和疫苗。