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主营:二抗,重组蛋白,细胞和组织裂解液,细胞涂片,组织切片,多肽
℡ 4000-520-616
℡ 4000-520-616
Prosci/Betatrophin Recombinant Protein/90-325/10 ug
产品编号:90-325
市  场 价:¥8500.00
场      地:美国(厂家直采)
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$425.00
品      牌: ProSci
公      司:ProSci Inc
公司分类:
Prosci/Betatrophin Recombinant Protein/90-325/10 ug
商品介绍

Specifications

SPECIES:Human
SOURCESPECIES:HEK293cells
SEQUENCE:Humanbetatrophin(22-198)isfusedattheC-terminustotheFcportionofhumanIgG1.
FUSIONTAG:FcTag
TESTEDAPPLICATIONS:
APPLICATIONS:Thisrecombinantproteinsisforresearchuseonly.
BIOLOGICALACTIVITY:N/A

Properties

PURITY:>90%(SDS-PAGE)
PHYSICALSTATE:Lyophilized
BUFFER:ContainsPBS+0.02%CHAPS.
CONCENTRATION:0.1mg/mlafterreconstitution.
STORAGECONDITIONS:Stableforatleast6monthsafterreceiptwhenstoredat-20˚C.

AdditionalInfo

ALTERNATENAMES:Angiopoietin-likeProtein8,ANGPTL8,Lipasin,Refeeding-inducedFatandLiverProtein,RIFL
ACCESSIONNO.:Q6UXH0
PROTEINGINO.:291219911

Background

Betatrophin(RIFL;Lipasin;Angiopoietin-likeprotein8(ANGPTL8))isanewlydiscoveredsecretedproteinof198aathatwasproposedtopromotebetacellproliferationandimproveglucosetoleranceinmice.Betatrophinmayalsofunctionininhibitionoflipaseactivityandonserumtriglycerideregulation.BetatrophinisexpressedintheliverandinwhiteandbrownADIposetissueofmice.Inhumans,betatrophinisfoundtobepredominantlyexpressedintheliver.Betatrophinlevelsarereducedbyfastingandareelevateduponinsulinresistanceandduringpregnancy.Betatrophin,accordingtopreliminarydatacouldbindtothemacrophagereceptorMarcoandalsotoRTN4R,aneuronalreceptor.Recently,astudyusingANGPTL8KOmiceshowedthatANGPTL8/Betatrophindoesnotplayaroleinbetacellproliferationnoringlycemiccontrolaspreviouslythought,butregulatesplasmatriglyceridelevels.
品牌介绍

ProSci Inc.始终开放以支持研究需求,同时确保我们员工的健康和安全。ProSci拥有广泛的冠状病毒SARS-CoV-2 重组蛋白和抗体产品组合,  并将继续积极开发新的冠状病毒  产品。此外,ProSci的定制抗体服务也保持开放状态,以支持研究团体开发  研究工具,诊断,疗法和疫苗。

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